ULCERGARD is the only proven, and FDA-approved, prevention for equine stomach ulcers. Unlike H2 blockers, antacids, nutritional supplements and other omeprazole-based products being marketed without FDA approval for preventing equine stomach ulcers, only ULCERGARD contains specially formulated omeprazole that blocks acid production at its source – the acid pump. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. And one dose lasts 24 hours. Watch how ULCERGARD works

Why is FDA approval important to your horse?

Simply put, it means peace of mind. From start to finish, FDA-approved drugs have been thoroughly tested for both safety and effectiveness:1

  • The safety and efficacy of the product is based on thorough scientific review prior to approval1
  • The product meets quality, purity and potency specifications1
  • Each unit is consistently manufactured under what are called "Good Manufacturing Practices"1
  • The drug is continually monitored by the FDA after it is on the market to ensure product performance, as well as identify any concerns or questions1
  • Even if these drugs are not manufactured in the United States, the facilities where they are made are still subject to FDA approval and inspection.2

There is no "generic" ULCERGARD

Illegally manufactured omeprazole products which many horse owners assume are legitimate generics of ULCERGARD have underperformed versus the FDA-approved product and have been found to vary widely in the amount of omeprazole they actually contain.3,4 In fact, when a product manufactured under the name of GastroMax3 was evaluated by UC Davis, it contained less than two-thirds of the omeprazole than its label claimed.5

When it comes to stability and efficacy, compounded omeprazole pastes simply don’t measure up. In a 60-day study of five compounded pastes, formulations started as low as 63% of labeled concentration on day 0, and dipped to as low as 17% by day 60, and were ineffective in promoting the healing of stomach ulcers in horses.3 If it’s not stable in a lab environment, how could it possibly survive a barn setting? GASTROGARD concentrations remained stable throughout the study.

What this means is that if you are using an illegally manufactured product, you are likely not getting all of the drug you’ve paid for – and your horse is likely getting an ineffective dose.


We followed the veterinarian’s advice and started giving Bootz ULCERGARD® (omeprazole) a couple of days before shows and during shows. During the 2012 show season, we didn’t have any of the problems we’ve had in the past keeping his weight on and with his willingness to work. And the only difference is that we’ve been giving him ULCERGARD.

Sarah Harnish, Pequea, PA

Owner/Rider of Hobbys Best Yet (Bootz), American Paint Horse Association

I use ULCERGARD® (omeprazole) a few days before we leave for a show, and through the entire event. After all the work, time and effort that goes into getting these horses to their peak, I want to give them every advantage, and that includes preventing ulcers.

Ron Stratton, Bristol, TN

American Quarter Horse Association judge and Professional Horseman

Nicki seemed much more comfortable and willing to do his job following the treatment. We were just excited that the stomach ulcers wouldn’t keep him from living up to his potential. We really believe the use of ULCERGARD® (omeprazole) with our horse contributed to this incredible accomplishment.

Lori Bailey

Owner, Sea-Vu Noble Aire (Nicki) 2012 Reserve Grand National Champion, Road Hack Hunter Seat
IMPORTANT SAFETY INFORMATION: ULCERGARD can be used in horses that weigh at least 600 pounds. Safety in pregnant mares has not been determined.
CAUTION: Safety of GASTROGARD in pregnant or lactating mares has not been determined. For prescribing information click here.
*When administered for 8 or 28 days, ULCERGARD is proven to effectively prevent gastric ulcers in horses exposed to stressful conditions.
1 Animal Health Institute and American Veterinary Medical Association and American Veterinary Distributors Association. Veterinary Compounding Guidelines. 2005. Available at: http://www.aaep.org/pdfs/drug_compounding_guidelines.pdf. Accessed February 20, 2010.
2 U.S. Department of Health and Human Services. Food and Drug Administration. FDA Basics. How does FDA oversee domestic and foreign drug manufacturing? Available at: http://www.fda.gov/AboutFDA/Transparency/Basics/ucm194989.htm. Accessed February 29, 2012.
3 Stanley SD, Knych HK. Comparison of Pharmaceutical Equivalence for Commercially Available Preparations of Omeprazole. AAEP Proceedings. 2011;57:63.
4 Nieto JE, et al. Comparison of paste and suspension formulations of omeprazole in the healing of gastric ulcers in racehorses in active training. J Am Vet Med Assoc. 2002;8:1-5.
5 Data on file at Merial.
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